DataSet Record GDS4299: Expression Profiles Data Analysis Tools Sample Subsets
Title: Early T-cell precursor acute lymphoblastic leukemia
Cluster AnalysisGDS4299 Cluster Image
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Summary: Analysis of tumor cells from pediatric patients with early T-cell precursor acute lymphoblastic leukemia (ETP ALL). The ETP ALL subtype has a poor prognosis when treated with standard chemotherapy. Results provide insight into the molecular mechanisms underlying ETP ALL.
Organism: Homo sapiens
Platform: GPL13158: [HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate
Citations:
  • Zhang J, Ding L, Holmfeldt L, Wu G et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 2012 Jan 11;481(7380):157-63. PMID: 22237106
  • Gutierrez A, Kentsis A, Sanda T, Holmfeldt L et al. The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia. Blood 2011 Oct 13;118(15):4169-73. PMID: 21878675
Reference Series: GSE28703 Sample count: 52
Value type: transformed count Series published: 2011/11/23