3-Deazaneplanocin A effect on multiple myeloma cells
Summary:
Analysis of MM cell lines (KMS18, MM.1S, NCI-H929, OPM-2) exposed to 500nM 3-Deazaneplanocin A (DZNep). DZNep potently inhibited growth and induced apoptosis in the NCI-H929 and MM.1S cell lines. Results provide insight into the molecular mechanisms underlying DZNep-induced apoptosis in MM cells.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Xie Z, Bi C, Cheong LL, Liu SC et al. Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells. PLoS One 2011;6(6):e21583. PMID: 21720561
