DataSet Record GDS4285: Expression Profiles Data Analysis Tools Sample Subsets
Title: Core binding factor-acute myeloid leukemia patients: mononuclear cells
Cluster AnalysisGDS4285 Cluster Image
Download
Summary: Analysis of mononuclear cells isolated from untreated, CBF-AML patients representing t(8;21) and inv(16)/t(16;16) karyotypes. The CBF-AML samples exhibited differential sensitivity to treatment with ABT-737 and BV6. Results provide insight into molecular basis of sensitivity to inhibitor treatment.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
  • Lück SC, Russ AC, Botzenhardt U, Paschka P et al. Deregulated apoptosis signaling in core-binding factor leukemia differentiates clinically relevant, molecular marker-independent subgroups. Leukemia 2011 Nov;25(11):1728-38. PMID: 21701487
Reference Series: GSE29883 Sample count: 12
Value type: transformed count Series published: 2011/06/11