Highly Active Antiretroviral Therapy (HAART) interruption effect on HIV patients: jejunal mucosa
Summary:
Analysis of gut biopsies from HIV+ patients following interruption of HAART. Gut-associated lymphoid tissue (GALT) is a critical host-pathogen interaction site in HIV infection. Results provide insight into molecular basis of host response to viral rebound in GALT following HAART interruption.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Lerner P, Guadalupe M, Donovan R, Hung J et al. The gut mucosal viral reservoir in HIV-infected patients is not the major source of rebound plasma viremia following interruption of highly active antiretroviral therapy. J Virol 2011 May;85(10):4772-82. PMID: 21345945