Programmed Death-1-expressing CD8 T cells in healthy adult peripheral blood
Summary:
Analysis of PD-1hi, PD-1lo, and naive CD8+CD3+ T cells FACS-sorted from peripheral blood of healthy adults. PD-1, a member of the CD28 family of immune modulators, is highly expressed on chronic virus-specific CD8 T cells. Results provide insight into PD-1-expressing CD8 T cells in healthy adults.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Duraiswamy J, Ibegbu CC, Masopust D, Miller JD et al. Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults. J Immunol 2011 Apr 1;186(7):4200-12. PMID: 21383243
