Isoflavone and 3,3’-diindolylmethane effect on C4-2B prostate cancer cells
Summary:
Analysis of C4-2B prostate cancer (PCa) cells treated with isoflavone (IsoF) and 3,3’- diindolylmethane (B-DIM) for up to 72 hours. IsoF and B-DIM inhibited the signal transductions in PCa signaling. Results provide insight into molecular mechanisms underlying PCa growth.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Li Y, Kong D, Ahmad A, Bao B et al. Targeting bone remodeling by isoflavone and 3,3'-diindolylmethane in the context of prostate cancer bone metastasis. PLoS One 2012;7(3):e33011. PMID: 22412975
