GATA3 ectopic expression effect on MDA-MB-231 breast cancer cells
Summary:
Analysis of MDA-MB-231 cells transduced with a lentivirus expressing GATA3. Luminal transcriptional regulator GATA3 reduces tumorigenicity and metastases of basal triple negative breast cancers (TNBC). Results provide insight into molecular basis of GATA3-mediated reduction of TNBC metastases.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Chu IM, Michalowski AM, Hoenerhoff M, Szauter KM et al. GATA3 inhibits lysyl oxidase-mediated metastases of human basal triple-negative breast cancer cells. Oncogene 2012 Apr 19;31(16):2017-27. PMID: 21892208
