Analysis of estrogen receptor (ER)+PEO4 or ER-2008 human epithelial ovarian cancer (EOC) cells laser captured from intraperitoneal xenografts of mice treated with estrogen (E2). Menopausal E2 replacement therapy increases risk of ER+ EOC. Results provide insight into E2 effects on tumor promotion.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Spillman MA, Manning NG, Dye WW, Sartorius CA et al. Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis. Cancer Res 2010 Nov 1;70(21):8927-36. PMID: 20959477