Shiga toxin type 1 effect on myelogenous leukemia cell line THP-1
Summary:
Analysis of macrophage-like THP-1 cells treated with Stx1 or lipopolysaccharides (LPS). Shiga toxins (Stxs) are bacterial cytotoxins produced by enteric pathogens Shigella dysenteriae and some serotypes of E. coli. Results provide further insight into the effects of Stxs on cell function.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Leyva-Illades D, Cherla RP, Galindo CL, Chopra AK et al. Global transcriptional response of macrophage-like THP-1 cells to Shiga toxin type 1. Infect Immun 2010 Jun;78(6):2454-65. PMID: 20351145
