Type 2 diabetic (TALLYHO/JngJ x C57BL6) F2 males: liver, pancreas, muscle and adipose tissue
Summary:
Analysis of various tissues from TH x B6 F2 males with high triglycerides. TH mice are a polygenic model for type 2 diabetes (T2D) characterized by obesity, insulin resistance, and hyperlipidemia. Results provide insight into quantitative trait loci (QTLs) affecting hypertriglyceridemia in TH mice.
Stewart TP, Kim HY, Saxton AM, Kim JH. Genetic and genomic analysis of hyperlipidemia, obesity and diabetes using (C57BL/6J × TALLYHO/JngJ) F2 mice. BMC Genomics 2010 Dec 19;11:713. PMID: 21167066
