High-fat dietary restriction effect on epididymal white adipose tissue
Summary:
Analysis of epididymal WAT from C57BL/6J adult males adapted to a high-fat diet for 3 wks, then fed a high-fat diet on an ad-libitum basis (HF-AL) or on a restricted basis (HF-DR) for 12 wks. Results provide insight into molecular mechanisms underlying improved metabolic health induced by HF-DR.
Duivenvoorde LP, van Schothorst EM, Bunschoten A, Keijer J. Dietary restriction of mice on a high-fat diet induces substrate efficiency and improves metabolic health. J Mol Endocrinol 2011 Aug;47(1):81-97. PMID: 21830320