DataSet Record GDS3944: Expression Profiles Data Analysis Tools Sample Subsets
Title: Rho kinase inhibitor fasudil effect on forebrain astrocyte culture: time course
Cluster AnalysisGDS3944 Cluster Image
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Summary: Analysis of astrocytes treated with Rho kinase (ROCK) inhibitor fasudil for up to 24 hrs. ROCK inhibitors inhibit glial scarring, a reactive process involving astrogliosis that occurs after injury to CNS. Results provide mechanistic insights into beneficial action of fasudil during brain injury.
Organism: Mus musculus
Platform: GPL6885: Illumina MouseRef-8 v2.0 expression beadchip
Citation:
  • Lau CL, Perreau VM, Chen MJ, Cate HS et al. Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor fasudil reveals cytoskeletal and pro-survival responses. J Cell Physiol 2012 Mar;227(3):1199-211. PMID: 21604263
Reference Series: GSE25829 Sample count: 32
Value type: transformed count Series published: 2011/05/10