Analysis of parietal cortices of young and aged F344 males implanted with telemetry devices to measure sleep architecture. Animals were trained in the Morris water maze to assess cognitive function. Results provide insight into possible mechanistic links between sleep changes and cognitive aging.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Buechel HM, Popovic J, Searcy JL, Porter NM et al. Deep sleep and parietal cortex gene expression changes are related to cognitive deficits with age. PLoS One 2011 Apr 4;6(4):e18387. PMID: 21483696
