HNF4A deficiency effect on embryonic stem cell model of hepatocyte differentiation
Summary:
Analysis of H9 (WAO9) embryonic stem (ES) cells subjected to hepatic differentiation protocol. ES-derived hepatocytes depleted of nuclear hormone receptor HNF4A also examined. Results provide insight into the role of HNF4A during the formation of hepatocytes from pluripotent stem cells.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
DeLaForest A, Nagaoka M, Si-Tayeb K, Noto FK et al. HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells. Development 2011 Oct;138(19):4143-53. PMID: 21852396
