Recombinant human growth hormone effect on lactating mammary gland: time course
Summary:
Analysis of milk fat globule from milk samples collected from normal, lactating women every 3hr for 4 days (1 day of baseline/pre-rhGH administration and 3 days of high-dose rhGH administration). Results provide insight into potential molecular mechanisms for increasing milk production.
Maningat PD, Sen P, Rijnkels M, Hadsell DL et al. Short-term administration of rhGH increases markers of cellular proliferation but not milk protein gene expression in normal lactating women. Physiol Genomics 2011 Apr 27;43(8):381-91. PMID: 21205870