Prolonged exercise training effect on skeletal muscle from type 2 diabetes subjects
Summary:
Analysis of skeletal muscle biopsies from insulin-treated type 2 diabetes (T2D) subjects before/after exercise training, pre-diabetics and healthy controls. Results provide insight into the molecular basis of T2D, the role of mitochondrial dysfunction, and the effects of prolonged exercise training.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
van Tienen FH, Praet SF, de Feyter HM, van den Broek NM et al. Physical activity is the key determinant of skeletal muscle mitochondrial function in type 2 diabetes. J Clin Endocrinol Metab 2012 Sep;97(9):3261-9. PMID: 22802091