Comparison of induced pluripotent and embryonic stem cells
Summary:
Analysis of induced pluripotent stem (iPS) cells from somatic cells (melanocytes, fibroblasts, and hepatocytes) representing all 3 embryonic germ layers, embryonic stem (ES) cell lines (H1, H7, H9) and their embryoid bodies. Results suggest iPS cells retain a memory of the original somatic cells.
GPL10666:
Affymetrix Human Gene ST 1.0 Custom RefSeq CDF version 12 [CDF: HuGene10stv1_Hs_REFSEQ]
Citation:
Ohi Y, Qin H, Hong C, Blouin L et al. Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells. Nat Cell Biol 2011 May;13(5):541-9. PMID: 21499256