Spatial and temporal analysis of laser capture microdissected wild-type, CD1 embryonic kidney sections across 3 developmental time points (E11.5, E12.5, E15.5) representing early stages of nephron formation. Results provide insight into molecular mechanisms underlying the stages of nephrogenesis.
Georgas K, Rumballe B, Valerius MT, Chiu HS et al. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol 2009 Aug 15;332(2):273-86. PMID: 19501082