Estrogen effect on bone marrow-derived c-kit+ stem cells and CD44+ stromal cells
Summary:
Analysis of bone marrow (BM) c-kit+ stem cells (SCs) and CD44+ stromal cells (StroCs) after exposure to physiological dose of 17b-estradiol. Results provide insight into the role of estrogen in regulating the functional organization of the BM SC niche and into its role in cardiac repair.
Lemieux C, Cloutier I, Tanguay JF. Estrogen-induced gene expression in bone marrow c-kit+ stem cells and stromal cells: identification of specific biological processes involved in the functional organization of the stem cell niche. Stem Cells Dev 2008 Dec;17(6):1153-63. PMID: 19006456