Sebacic acid supplemented diet effect on db/db liver
Summary:
Analysis of livers of db/db animals fed a diet supplemented with sebacic acid (SA) for 6 weeks. SA supplementation improves fasting plasma glucose, HbA1c and glucose tolerance in this model of type 2 diabetes. Results provide insight into the mechanism of action of SA.
Membrez M, Chou CJ, Raymond F, Mansourian R et al. Six weeks' sebacic acid supplementation improves fasting plasma glucose, HbA1c and glucose tolerance in db/db mice. Diabetes Obes Metab 2010 Dec;12(12):1120-6. PMID: 20977585