DataSet Record GDS3795: Expression Profiles Data Analysis Tools Sample Subsets
Title: Myelodysplastic syndrome: CD34+ hematopoietic stem cells
Cluster AnalysisGDS3795 Cluster Image
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Summary: Analysis of bone marrow CD34+ hematopoietic stem cells of myelodysplastic syndrome (MDS) patients. MDS is a group of clonal hematopoietic stem cell malignancies characterized by ineffective hematopoiesis. Results provide insight into the molecular pathogenesis of MDS.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Pellagatti A, Cazzola M, Giagounidis A, Perry J et al. Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells. Leukemia 2010 Apr;24(4):756-64. PMID: 20220779
  • Gorombei P, Guidez F, Ganesan S, Chiquet M et al. BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome. Int J Mol Sci 2021 Sep 30;22(19). PMID: 34638998
Reference Series: GSE19429 Sample count: 200
Value type: count Series published: 2010/03/13