Transcription factor ETS-4 deletion effect on larvae
Summary:
Analysis of stage L4 larvae with two distinct deletion alleles of ets-4: ets-4(ok165) and ets-4(uz1). Adults with ets-4 mutations have a significant extension of mean life span. Results provide insight into the transcriptional control of aging effectors by the ETS-4 transcription factor.
GPL7272:
Agilent-012795 C. elegans Oligo Microarray G2518A Option 002 (Probe Name version)
Citation:
Thyagarajan B, Blaszczak AG, Chandler KJ, Watts JL et al. ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. PLoS Genet 2010 Sep 16;6(9):e1001125. PMID: 20862312
