Analysis of tracheal explants at 2hrs and 24hrs following brief exposure to whole smoke. Some of the explants were pretreated with dexamethasone prior to smoke exposure. Results provide insight into the molecular mechanisms underlying pathogenesis of cigarette smoke-induced small airway remodeling.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
López-Boado YS, Li JU, Clayton CL, Wright JL et al. Modification of the rat airway explant transcriptome by cigarette smoke. Inhal Toxicol 2010 Feb;22(3):234-44. PMID: 19883206