DataSet Record GDS3668: Expression Profiles Data Analysis Tools Sample Subsets
Title: Familial hypercholesterolemia and atherosclerosis: monocytes
Cluster AnalysisGDS3668 Cluster Image
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Summary: Analysis of monocytes (MO) from familial hypercholesterolemia (FH) patients. FH patients have a defective or missing LDLR resulting in atherosclerosis. Atherosclerotic lesions often contain MO-derived, lipid-laden macrophages. Results provide insight into the role of MO in onset of atherosclerosis.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
  • Mosig S, Rennert K, Büttner P, Krause S et al. Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism. BMC Med Genomics 2008 Nov 28;1:60. PMID: 19040724
Reference Series: GSE6054 Sample count: 23
Value type: count Series published: 2008/04/01