Cardiomyocyte response to various types of fatty acids in vitro
Summary:
Analysis of cardiomyocytes treated with 0.4 mM octanoate, palmitate, stearate, oleate, or linoleate for 24 hours. Studies suggest that distinct fatty acid species are cardiotoxic, while others are cardioprotective. Results provide insight into the molecular basis of these effects on the heart.
Lockridge JB, Sailors ML, Durgan DJ, Egbejimi O et al. Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. J Lipid Res 2008 Jul;49(7):1395-408. PMID: 18387886
