Spared nerve injury model of peripheral neuropathic pain: dorsal horn of spinal cord
Summary:
Analysis of adult and neonatal dorsal horns of spinal cords 7 days after spared nerve injury (SNI). SNI is a model for neuropathic pain (NP). Partial peripheral nerve injury in adults result in NP-like hypersensitivity, but not in neonates. Results provide insight into the molecular basis of NP.
GPL341:
[RAE230A] Affymetrix Rat Expression 230A Array
Citation:
Costigan M, Moss A, Latremoliere A, Johnston C et al. T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity. J Neurosci 2009 Nov 18;29(46):14415-22. PMID: 19923276
