DataSet Record GDS3600: Expression Profiles Data Analysis Tools Sample Subsets
Title: Endothelial cell response to estradiol in vitro
Cluster AnalysisGDS3600 Cluster Image
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Summary: Analysis of cultured umbilical vein endothelial cells treated with 1 nmol/L estradiol for 24 hours. The incidence of coronary heart disease in women increases after menopause. Results provide insight into the response of the cardiovascular system to estrogens at the molecular level.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Sobrino A, Mata M, Laguna-Fernandez A, Novella S et al. Estradiol stimulates vasodilatory and metabolic pathways in cultured human endothelial cells. PLoS One 2009 Dec 14;4(12):e8242. PMID: 20011585
  • Pérez-Cremades D, Mompeón A, Vidal-Gómez X, Hermenegildo C et al. miRNA as a New Regulatory Mechanism of Estrogen Vascular Action. Int J Mol Sci 2018 Feb 6;19(2). PMID: 29415433
Reference Series: GSE16683 Sample count: 6
Value type: count Series published: 2009/06/18