DataSet Record GDS3562: Expression Profiles Data Analysis Tools Sample Subsets
Title: Azithromycin effect on Pseudomonas aeruginosa PAO1
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Summary: Analysis of PAO1 cultures exposed to up to 2.0 ug/ml of the macrolide azithromycin (AZM) for 9 hours. Low-dose macrolides are effective therapy in patients with chronic lung infections such as those caused by P. aeruginosa. Results provide insight into mechanism of action of AZM against infection.
Organism: Pseudomonas aeruginosa
Platform: GPL84: [Pae_G1a] Affymetrix Pseudomonas aeruginosa Array
Citation:
  • Kai T, Tateda K, Kimura S, Ishii Y et al. A low concentration of azithromycin inhibits the mRNA expression of N-acyl homoserine lactone synthesis enzymes, upstream of lasI or rhlI, in Pseudomonas aeruginosa. Pulm Pharmacol Ther 2009 Dec;22(6):483-6. PMID: 19393329
Reference Series: GSE12738 Sample count: 5
Value type: count Series published: 2009/05/01