Transcription factor CREB depletion effect on myeloid leukemic cell line
Summary:
Analysis of myeloid leukemia K562 cells depleted for cAMP Response Element Binding Protein (CREB), a transcription factor. CREB is overexpressed in bone marrow samples of patients with acute leukemia. Results provides insight into the molecular mechanisms by which CREB contributes to acute leukemia.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Pellegrini M, Cheng JC, Voutila J, Judelson D et al. Expression profile of CREB knockdown in myeloid leukemia cells. BMC Cancer 2008 Sep 18;8:264. PMID: 18801183
