Conjugated linoleic acid isomers effect on intestinal cell line
Summary:
Analysis of intestinal Caco-2 cells treated with conjugated linoleic acid (CLA) isomer trans-10, cis-12 CLA or cis-9, trans-11 CLA. CLA exerts isomer-specific effects on transepithelial calcium transport and cell growth in Caco-2 cells. Results provide insight into molecular mechanisms of action.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Murphy EF, Hooiveld GJ, Muller M, Calogero RA et al. Conjugated linoleic acid alters global gene expression in human intestinal-like Caco-2 cells in an isomer-specific manner. J Nutr 2007 Nov;137(11):2359-65. PMID: 17951470