Analysis of renal proximal tubules dissected from CLCN5 deficient animals, a model for Dent disease. Clcn5 is a chloride/protein exchanger expressed in renal tubules. Results provide insight into the molecular pathophysiology of Dent disease.
Wright J, Morales MM, Sousa-Menzes J, Ornellas D et al. Transcriptional adaptation to Clcn5 knockout in proximal tubules of mouse kidney. Physiol Genomics 2008 May 13;33(3):341-54. PMID: 18349385