Analysis of kidneys of 1 week old animals lacking aquaporin-11 (AQP11). AQP11 null mutants develop polycystic kidneys. Results provide insight into the molecular basis of cyst formation in kidneys of AQP11 mutants.
Okada S, Misaka T, Tanaka Y, Matsumoto I et al. Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation. FASEB J 2008 Oct;22(10):3672-84. PMID: 18606867