Iron enriched and deficient diets effect on the liver
Summary:
Analysis of livers of C57BL/6 and DBA/2 animals fed an iron enriched or deficient diet. Iron induces the production of hepcidin, a hepatic peptide hormone that regulates systemic iron homeostasis. Results provide insight into the molecular mechanisms regulating hepcidin expression.
Kautz L, Meynard D, Monnier A, Darnaud V et al. Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver. Blood 2008 Aug 15;112(4):1503-9. PMID: 18539898
