Liver response to Pacific ciguatoxin-1: time course
Summary:
Analysis of adult male C57/BL6 livers exposed to a symptomatic dose of the marine neurotoxin Pacific ciguatoxin-1 (P-CTX-1) for up to 24 hours. Ciguatoxins (CTX) are polyether neurotoxins that target voltage-gated sodium channels. Results provide insight into the hepatic molecular response to CTX.
GPL2872:
Agilent-012694 Whole Mouse Genome G4122A (Feature Number version)
Citation:
Morey JS, Ryan JC, Bottein Dechraoui MY, Rezvani AH et al. Liver genomic responses to ciguatoxin: evidence for activation of phase I and phase II detoxification pathways following an acute hypothermic response in mice. Toxicol Sci 2008 Jun;103(2):298-310. PMID: 18353800
