Analysis of cervical cancer (CC) primary tumors and cell lines. Chromosomal amplification is a common cellular mechanism of gene activation in tumorigenesis; chromosome 20 is a commonly gained chromosome in CC. Results provide insight into the potential role of chromosome 20 gain in CC progression.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Scotto L, Narayan G, Nandula SV, Arias-Pulido H et al. Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression. Genes Chromosomes Cancer 2008 Sep;47(9):755-65. PMID: 18506748
