Analysis of C57BL/6 colon cultures treated with 10 ng/ml of interleukin-22 (IL-22) for 24 hours. IL-22, a member of the IL-10 family of cytokines, can induce a marked antimicrobial response in vitro. Results provide insight into the molecular basis of IL-22 induced host defense mechanisms.
GPL2872:
Agilent-012694 Whole Mouse Genome G4122A (Feature Number version)
Citation:
Zheng Y, Valdez PA, Danilenko DM, Hu Y et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat Med 2008 Mar;14(3):282-9. PMID: 18264109