Monocyte-derived dendritic cell response to VAF347
Summary:
Analysis of immature monocyte-derived dendritic cells following activation with anti-CD40 antibodies for 8 hours in the presence of VAF347. VAF347 is a low molecular weight compound that inhibits allergic lung inflammation in vivo. Results provide insight into the mechanism of action of VAF347.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Lawrence BP, Denison MS, Novak H, Vorderstrasse BA et al. Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. Blood 2008 Aug 15;112(4):1158-65. PMID: 18270326
