Analysis of retinas from adult protocadherin 21 (prCAD) mutants. The prCAD mutant is a model for inherited photoreceptor degeneration. prCAD is required for the assembly and integrity of the photoreceptor outer segment. Results compared with those from light damaged retinas (GDS3187).
Rattner A, Nathans J. The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia. J Neurosci 2005 May 4;25(18):4540-9. PMID: 15872101