Transcription factor AP-2 gamma mutation effect on the embryonic skin
Summary:
Analysis of back skin from embryonic day 16.5 animals bearing a mutation in transcription factor AP-2 gamma. The E16.5 AP-2 gamma mutants display abnormal epidermal stratification. Results provide insight into the role of AP-2 gamma in skin development.
Guttormsen J, Koster MI, Stevens JR, Roop DR et al. Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol 2008 May 1;317(1):187-95. PMID: 18353300