Male contraceptive agent Gamendazole effect on the testis: time course
Summary:
Analysis of testes of males treated with gamendazole for up to 24 hours. Gamendazole is a nonhormonal, nonsteroidal, oral indazole carboxylic acid contraceptive agent for males. The gamendazole analog lonidamine was also examined. Results provide insight into the mechanism of action of gamendazole.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Tash JS, Attardi B, Hild SA, Chakrasali R et al. A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose. Biol Reprod 2008 Jun;78(6):1127-38. PMID: 18218612
