DataSet Record GDS3125: Expression Profiles Data Analysis Tools Sample Subsets
Title: Radioresistant tumor response to ionizing radiation: time course
Cluster AnalysisGDS3125 Cluster Image
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Summary: Analysis of nu61 radioresistant tumors 5 and 24 hours following exposure to ionizing radiation. Nu61 tumors derived from the radiosensitive squamous cell carcinoma cell line SCC61. Results provide insight into the molecular basis of acquired tumor radioresistance.
Organism: Homo sapiens
Platform: GPL96: [HG-U133A] Affymetrix Human Genome U133A Array
Citations:
  • Khodarev NN, Beckett M, Labay E, Darga T et al. STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci U S A 2004 Feb 10;101(6):1714-9. PMID: 14755057
  • Khodarev NN, Minn AJ, Efimova EV, Darga TE et al. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res 2007 Oct 1;67(19):9214-20. PMID: 17909027
Reference Series: GSE9713 Sample count: 18
Value type: count Series published: 2007/11/28