Tumor suppressor PTEN depletion effect on various cell lines
Summary:
Analysis of A431, HCC827, and SKBR-3 carcinoma cell lines depleted for the tumor suppressor PTEN. Inactivation of PTEN is a common genetic lesion in cancer. Results provide insight into the molecular basis of the oncogenic phenotypes resulting from PTEN deficiency.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Vivanco I, Palaskas N, Tran C, Finn SP et al. Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN. Cancer Cell 2007 Jun;11(6):555-69. PMID: 17560336
