Splenocyte response to infection by virB mutant Brucella strains
Summary:
Analysis of splenocytes from animals infected with virB mutant Brucella arbortus strains. The virB operon encodes a Type IV secretion system (T4SS) essential for the intracellular survival and persistent infection by Brucella species. Results provide insight into the role of T4SS in infections.
Roux CM, Rolán HG, Santos RL, Beremand PD et al. Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice. Cell Microbiol 2007 Jul;9(7):1851-69. PMID: 17441987
