Organized and growth-arrested mammary acini: time course
Summary:
Temporal analysis of two nonmalignant mammary epithelial cells (HMEC) grown in a laminin-rich extracellular matrix. Both HMECs transit from a disorganized to an organized state to form polarized acini. Results identify gene signatures with potential value for breast cancer prognosis prediction.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Fournier MV, Martin KJ, Kenny PA, Xhaja K et al. Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer. Cancer Res 2006 Jul 15;66(14):7095-102. PMID: 16849555