Large airway epithelial cells from cigarette smokers with suspect lung cancer
Summary:
Analysis of large airway epithelial cells from cigarette smokers without cancer, with cancer, and with suspect lung cancer. Results provide insight into the feasibility of using gene expression to detect early stage lung cancer in smokers.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citations:
Spira A, Beane JE, Shah V, Steiling K et al. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med 2007 Mar;13(3):361-6. PMID: 17334370
Gustafson AM, Soldi R, Anderlind C, Scholand MB et al. Airway PI3K pathway activation is an early and reversible event in lung cancer development. Sci Transl Med 2010 Apr 7;2(26):26ra25. PMID: 20375364
