Estrogen effect on breast cancer cell line coexpressing estrogen receptors alpha and beta
Summary:
Analysis of estrogen receptor (ER) alpha positive MCF-7 breast cancer cells following introduction of ERbeta and treatment with estrogen. The majority of breast cancers express both ERalpha and ERbeta. Results provide insight into the comodulatory effects of these two ERs.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Chang EC, Frasor J, Komm B, Katzenellenbogen BS. Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells. Endocrinology 2006 Oct;147(10):4831-42. PMID: 16809442
