Analysis of livers from animals fed a ketogenic diet (KD). KDs, diets that are high in fat and low in carbohydrates, are used as an approach to weight loss. Results provide insight into the KD-induced molecular mechanisms underlying the metabolic state congruous with weight loss.
Kennedy AR, Pissios P, Otu H, Roberson R et al. A high-fat, ketogenic diet induces a unique metabolic state in mice. Am J Physiol Endocrinol Metab 2007 Jun;292(6):E1724-39. PMID: 17299079