Retinoblastoma binding protein RBP2 deficiency effect on embryonic fibroblasts
Summary:
Analysis of embryonic fibroblasts lacking the retinoblastoma binding protein RBP2. RBP2 contains a histone demethylase signature motif, as well as other domains frequently found in transcriptional regulators. Results provide mechanistic insights into transcriptional regulation by RBP2.
Klose RJ, Yan Q, Tothova Z, Yamane K et al. The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell 2007 Mar 9;128(5):889-900. PMID: 17320163
