Banded hedgehog effect on the pronephric nephron development
Summary:
Analysis of pronephric explants dissected from embryos previously injected with banded hedgehog mRNA. Hedgehog suppresses the development of the pronephric kidney tubule but not that of the pronephric glomus. Results provide insight into the molecular basis of this inhibitory effect.
Urban AE, Zhou X, Ungos JM, Raible DW et al. FGF is essential for both condensation and mesenchymal-epithelial transition stages of pronephric kidney tubule development. Dev Biol 2006 Sep 1;297(1):103-17. PMID: 16872594
