DataSet Record GDS2542: Expression Profiles Data Analysis Tools Sample Subsets
Title: Heart failure in obesity model
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Summary: Analysis of left heart ventricles of 4 and 10-month old SHHF obese animals homozygous for leptin receptor (ObR) mutation. This mutant is obese at 4 months of age and prone to heart failure after 14 months. Results provide insight into molecular basis of the contribution of obesity to heart failure.
Organism: Rattus norvegicus
Platform: GPL2580: rzpd rat
Citation:
  • Roncalli J, Smih F, Desmoulin F, Dumonteil N et al. NMR and cDNA array analysis prior to heart failure reveals an increase of unsaturated lipids, a glutamine/glutamate ratio decrease and a specific transcriptome adaptation in obese rat heart. J Mol Cell Cardiol 2007 Mar;42(3):526-39. PMID: 17222424
Reference Series: GSE2876 Sample count: 20
Value type: count Series published: 2006/07/05